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Making sense of socially enhanced aggression in the brain

July 22, 2022 by

Researchers have identified the brain regions responsible for the increased aggression that occurs when male mice spend time with other male mice before an aggressive encounter -- a concept known as social instigation. When social instigation occurs, cells in the lateral habenula signal to the dorsal raphe nucleus, which then communicates with the ventral tegmental area, leading to heightened aggression. These findings may have applications for socially provoked anger or violence.

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