Home » Entries posted by NewsBot (Page 275)

In the quest for a TBI therapy, astrocytes may be the bull’s-eye

New studies show what happens when an enzyme called monoacylglycerol lipase (MAGL) is genetically inactivated in experimental mice. Typically, MAGL breaks down a neuroprotective molecule called 2-arachidonoylglycerol (2-AG), diminishing the latter’s be…

Insight into the genetics of autism offers hope for new drug treatments

Drugs to increase insulin signaling may be effective for treating autism, say researchers who have discovered how a genetic change impacts on insulin signaling and glucose metabolism in the brain.

Exploring the signals that underlie learning

When you start learning how to do something new, like playing a musical instrument, the simplest tasks can feel difficult. But as you gain experience, you play with ease and without conscious thought. Researchers are mapping the signals that correlate …

Illuminating real-time brain dynamics of neuropeptides with a fluorescent biosensor

Neuropeptides play fundamental roles in modulating cellular and circuit functions within the brain. One such signaling molecule — orexin — regulates arousal and wakefulness, and its failure can lead to constant daytime sleepiness (narcolepsy). Resear…

New mechanism involved in learning and memory

FMRP, a protein whose loss causes intellectual disability, may regulate a neuron’s synaptic response by establishing a feedback loop between the cell’s nucleus and its faraway dendrites.

Neurobiological processes occurring during puberty that trigger sex differences in learning and memory

New research reveals that sex differences in learning and memory mechanisms are triggered by biological events occurring during puberty. Findings show prepubescent female rodents have much better hippocampal long-term potentiation (LTP) and spatial lea…

How does cannabis use affect brain health? Caution advised, more research needed, experts say

Although recreational and medicinal marijuana (cannabis) is increasingly available across the U.S., public and professional awareness that cannabis use may adversely affect brain health is critical, according to the American Heart Association’s first s…

Newly discovered effect of toxic goiter on brain

Toxic goiter affects the brain more than was previously known, a new study shows, and involves volume changes occurring in central parts of the brain. These findings are described as a key advance for a vulnerable group of patients.

Amylin peptide in the brain senses isolation and drives social contact-seeking behavior

In efforts to understand the neural basis for loneliness, researchers have found a molecular indicator and regulator of social isolation in female mice. The new study reports that social contact-seeking behavior in mice is driven by the peptide amylin …

Genetically informed atlases reveal new landscapes in brain structure

Scientists have used atlases of the human brain informed by genetics to identify hundreds of genomic loci. The findings illuminate how genes impact the brain and diseases.