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Eyes provide peek at Alzheimer’s disease risk

Amyloid plaques found in the retinas of eyes may be an indicator of similar plaques in the brain, a hallmark of Alzheimer’s disease, and may provide a more visible biomarker for detecting disease risk.

Possible antidote for club drug GHB overdose

Diclofenac and other NSAIDs may limit the passage of narcolepsy medication and illicit party drug GHB to the brain, decreasing the potential for fatal overdose, researchers find.

Think leisure is a waste? That may not bode well for your mental health

Feeling like leisure is wasteful and unproductive may lead to less happiness and higher levels of stress and depression, new research suggests.

From mathematics to medicine: Applying complex mathematics to analyze fMRI data

Mathematical research is aiding in the analysis of fMRI data. fMRI is the preeminent class of signals collected from the brain in vivo and is irreplaceable in the study of brain dysfunction in many medical fields, including psychiatry, neurology and pe…

Sounds and words are processed separately and simultaneously in the brain

After years of research, neuroscientists have discovered a new pathway in the human brain that processes the sounds of language. The findings suggest that auditory and speech processing occur in parallel, contradicting a long-held theory that the brain…

Genome-editing strategy developed for potential Alzheimer’s disease therapy

Scientists have developed a novel strategy using brain-wide genome-editing technology that can reduce Alzheimer’s disease(AD) pathologies in genetically modified AD mouse models. This advanced technology offers immense potential to be translated as a n…

Histamine could be a key player in depression, according to study in mice

Bodily inflammation dampens levels of a ‘feel-good molecule’ and antidepressants’ ability to boost them, according to new research in mice.

Brain organoids develop optic cups that respond to light

Human induced pluripotent stem cells (iPSCs) can be used to generate brain organoids containing an eye structure called the optic cup, according to a new study. The organoids spontaneously developed bilaterally symmetric optic cups from the front of th…

Mutated enzyme weakens connection between brain cells that help control movement

In one type of a rare, inherited genetic disorder that affects control of body movement, scientists have found a mutation in an enzyme impairs communication between neurons and what should be the inherent ability to pick up our pace when we need to run…

A defective potassium channel disrupts the brain’s navigation system

The potassium channel KCNQ3 is required for our brain to generate accurate spatial maps. In mice, defects in KCNQ3 function have measurable effects on the internal navigation system.