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Study reveals activity of navtemadlin in glioblastoma, points to possible treatment improvements

Clinical research suggests that combining a novel agent called navtemadlin with DNA-damaging chemotherapy for the treatment of glioblastoma, a form of brain cancer, could increase efficacy. Navtemadlin is an MDM2 inhibitor that can help to kill cancer …

Mutation increases enzyme in mouse brains linked to schizophrenia behaviors

A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct genetic link to psychosis, report researchers.

Scientists solve the brain’s motion-source separation problem

Neuroscientists have discovered how the brain distinguishes between visual motion occurring in the external world from that caused by the observer moving through it. Known as the ‘motion-source separation problem,’ researchers have long wondered how th…

‘Healthy’ vitamin B12 levels not enough to ward off neuro decline

Meeting the minimum requirement for vitamin B12, needed to make DNA, red blood cells and nerve tissue, may not actually be enough — particularly if you are older. It may even put you at risk for cognitive impairment.

Newfound circuit better explains how the brain recognizes what is familiar and important

A newly identified part of a brain circuit mixes sensory information, memories, and emotions to tell whether things are familiar or new, and important or just ‘background noise.’

A geometric deep learning method for decoding brain dynamics

Scientists have developed a geometric deep learning method that can create a coherent picture of neuronal population activity during cognitive and motor tasks across experimental subjects and conditions.

Group childcare positively affects toddler development

Many Japanese mothers are reluctant to send their children to childcare before the age of three due to the ‘Three-Year-Old Myth,’ which suggests that healthy development requires a child to stay at home and be raised by their mother. However, a recent …

Study maps new brain regions behind intended speech

Imagine seeing a furry, four-legged animal that meows. Mentally, you know what it is, but the word ‘cat’ is stuck on the tip of your tongue. This phenomenon, known as Broca’s aphasia or expressive aphasia, is a language disorder that affects a person’s…

Scientists find key differences in male, female responses to stress

A new study led by researchers at UF Health has uncovered why males and females may experience stress differently.

Researchers identify a brain circuit for creativity

Researchers analyzed data from 857 patients across 36 fMRI brain imaging studies and mapped a common brain circuit for creativity.