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A comprehensive map of how Alzheimer’s affects the brain

Researchers performed the first comprehensive analysis of the genes altered in individual brain cells of patients with Alzheimer’s disease, allowing them to identify the distinctive cellular pathways affected in neurons and other types of brain cells.

Unanticipated early origins of childhood brain cancer

Brain tumors are the leading cause of non-accidental death in children in Canada, but little is known about when these tumours form or how they develop. Researchers have recently identified the cells that are thought to give rise to certain brain tumor…

Do you smell what I smell?

A new study sheds light on understanding the extensive individual differences in how we sense odors. By showing that small changes in a single olfactory receptor gene can affect how strong and pleasant a person finds an odor, the findings expand unders…

Drug can reverse hyperactivity induced by parasitic infection

When rodents get infected by Toxoplasma gondii, the single-celled brain parasite that causes toxoplasmosis, they become hyperactive risk-takers. Researchers show for the first time that it’s possible to reverse that behavioral change.

Researchers define Alzheimer’s-like brain disorder

A brain disorder that mimics symptoms of Alzheimer’s disease has been defined with recommended diagnostic criteria and guidelines for advancing future research on the condition.

How the brain integrates sensory input

Hearing, sight, touch – our brain captures a wide range of distinct sensory stimuli and links them together. The brain has a kind of built-in filter function for this: sensory impressions are only integrated if it is necessary and useful for the task a…

Experts draft guidelines for Alzheimer’s-like condition

Experts have defined an under-recognized, newly named condition that mimics Alzheimer’s disease and propose guidelines for diagnosing and researching it.

Gender impacts brain activity in alcoholics, study finds

A new study finds that compared to alcoholic women, alcoholic men have more diminished brain activity in areas responsible for emotional processing, as well as memory and social processing among other functions.

Do ‘microglia’ hold the key to stop Alzheimer’s disease?

Scientists have studied how specialized brain cells called microglia respond to the accumulation of toxic proteins in the brain, a feature typical of Alzheimer’s. The three major disease risk factors for Alzheimer’s — age, sex and genetics — all affe…

Possible link between autism and antidepressants use during pregnancy

An international team has found a potential link between autistic-like behavior in adult mice and exposure to a common antidepressant in the womb. They also identified a treatment that helped improve memory loss and social interactions, according to th…