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Brain’s ‘escape switch’ controlled by threat sensitivity dial

Neuroscientists have discovered how the brain bidirectionally controls sensitivity to threats to initiate and complete escape behaviour in mice. These findings could help unlock new directions for discovering therapies for anxiety and post-traumatic st…

Researchers identify vascular changes in the brain linked to Alzheimer’s disease

The blood-brain barrier — a network of blood vessels and tissues that nurtures and protects the brain from harmful substances circulating in the blood — is disrupted in Alzheimer’s disease. Now, researchers have uncovered unique molecular signatures …

Light-weight microscope captures large-scale brain activity of mice on the move

With a new microscope that’s as light as a penny, researchers can now observe broad swaths of the brain in action as mice move about and interact with their environments.

Personalized magnetic stimulation may help in treating depression

Not all patients with depression respond to medication. Two recently published studies provide additional information on how an alternative treatment, transcranial magnetic stimulation (TMS), could be further enhanced. Researchers developed more precis…

The hippocampus, the cerebral conductor of our daily priorities

How does our brain distinguish between urgent and less urgent goals? Researchers explored how our brain remembers and adjusts the goals we set ourselves on a daily basis. Their study reveals differences in the way we process immediate and distant goals…

Resiliency shaped by activity in the gut microbiome and brain

A new study has found that resilient people exhibit neural activity in the brain regions associated with improved cognition and regulating of emotions, and were more mindful and better at describing their feelings.

Research finds causal evidence tying cerebral small-vessel disease to Alzheimer’s, dementia

While previous studies suggested an association of the most common cerebral small-vessel disease with dementia risk, new research provides evidence of causal link, identifying it as a major vascular factor.

Unlocking the entrepreneurial brain: New perspectives on cognitive flexibility

Pioneering research highlights the importance of combining neuroscience with traditional entrepreneurial studies to gain a comprehensive understanding of what makes successful entrepreneurs distinct at a neurological level.

Removal of ovaries before menopause associated with reduced white matter in brain

Women who have their ovaries removed before menopause, particularly before the age of 40, have reduced white matter integrity in multiple regions of the brain later in life, a new study suggests. White matter refers to the nerve fibers that connect neu…

Shining light on mental health in space science community

The severity of anxiety and depressive symptoms in the planetary science community is greater than in the general U.S. population, according to a new study.