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Disproving hypothesis clears path for research for new treatment options for schizophrenia

Researchers reported results from the first repeated-dose study of a dopamine-1 receptor (D1R) agonist for treating the cognitive and negative symptoms of schizophrenia yesterday in the Journal of…

New studies of the ‘natural history’ of schizophrenia raise hope for new treatments

Emerging evidence on the development, ‘prodromal’ characteristics, and long-term course of schizophrenia provide reasons for optimism for developing new treatments and preventive approaches for this devastating disorder, according to new research.

Patterns of brain swelling may explain susceptibility of children to cerebral malaria

Brain swelling is a strong predictor of death in children with cerebral malaria (a severe form of the disease where parasites have accumulated in brain vessels), and also in mice with experimental cerebral malaria. A high-resolution whole brain imaging…

Grid cells’ role in human imagination revealed

Evidence of grid cell activity has been seen in healthy volunteers asked to imagine moving through an environment. The study used fMRI scans to detect brain activity consistent with grid cell activity in the entorhinal cortex, an important ‘hub’ for na…

Super-clear synapses at super resolutions

Researchers have developed a way to obtain super-resolution 3-D images of delicate structures deep in the brain.The work describes a new process for making brain tissue transparent that outperforms other methods and allows extremely detailed imaging of…

Blame your noisy brain for misses and fumbles

No matter how much we practice a given movement, it will still be imperfect. The reason for this frustration, according to a new study by neuroscientists, is in how we sense the world. A given individual neuron varies in its activity even when we see e…

Scientists watch activity of newborn brain cells in mice; reveal they are required for memory

Neuroscientists have described the activity of newly generated brain cells in awake mice — a process known as adult neurogenesis — and revealed the critical role these cells play in forming memories. The new research also offers clues as to what happ…

Oxytocin can improve compassion in people with symptoms of PTSD

Oxytocin — “the love hormone” — may enhance compassion of people suffering from symptoms of post-traumatic stress disorder (PTSD), according to new study. Compassion is pro-social motivation to help others who are in distress. It is an outcome of emo…

Researchers optimize methods to study neurons during motor activity

Researchers have optimized the techniques for studying motor learning in order to repeatedly assess the activity of neurons for days, weeks, or even months. These sophisticated approaches allow the further characterization of the neurons that are conti…

Society can have a strong influence on how honest we are, says a new study

The societies we live in can have a direct influence on how dishonest people may be, according to a new study from The University of Nottingham.