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Metformin’s hidden brain pathway revealed after 60 years

A major discovery reveals that metformin works not just in the body, but in the brain. By switching off a key protein and activating specific neurons, the drug lowers blood sugar through a previously hidden pathway, opening new doors for diabetes treat…

Fathers face rising depression risk a year after baby arrives

New fathers appear to have fewer mental health diagnoses during pregnancy and the early months after birth. But that early stability does not last. About a year later, depression and stress-related disorders increase significantly, surprising researche…

Weight loss drug Ozempic cuts depression, anxiety, and addiction risk

GLP-1 medications like semaglutide (Ozempic) may offer unexpected mental health benefits alongside weight loss. A large study found major drops in depression, anxiety, and psychiatric-related hospital visits among users. Even substance use disorders we…

Huge study finds no evidence cannabis helps anxiety, depression, or PTSD

The largest review of medicinal cannabis to date found it doesn’t effectively treat anxiety, depression, or PTSD—despite millions using it for those reasons. Researchers warn it could even make mental health worse, raising risks like psychosis and …

Scientists link childhood stress to lifelong digestive issues

Early life stress may set the stage for long-term digestive problems by disrupting the gut-brain connection. Studies in both mice and thousands of children found links to symptoms like pain, constipation, and IBS. Scientists discovered that different b…

Microplastics may be quietly damaging your brain and fueling Alzheimer’s and Parkinson’s

Tiny plastic particles may be quietly threatening brain health. New research suggests microplastics—now widely found in food, water, and even household dust—could trigger inflammation and damage in the brain through multiple biological pathways. Sc…

Depression may start with an energy problem in brain cells

Researchers have discovered a surprising change in how cells produce energy in people with depression. Brain and blood cells in young adults with major depressive disorder produced more energy molecules at rest but had trouble increasing energy product…

Brain scans reveal how ketamine quickly lifts severe depression

A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor that helps neurons communicate and found that ketamine …

A new “magic mushroom” drug could treat depression without psychedelic hallucinations

Scientists are exploring a new way to harness the medical promise of psychedelic compounds without the mind-bending side effects. Researchers created modified versions of psilocin — the active form of psilocybin from “magic mushrooms” — that st…

Golden Retriever genes linked to anxiety, aggression, and intelligence in humans

Scientists studying 1,300 golden retrievers have uncovered genetic clues explaining why some dogs are more anxious, energetic, or aggressive than others. Remarkably, several of the same genes linked to canine behavior are also tied to human traits like…