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Scientists uncover key brain pathway mediating panic disorder symptoms

Researchers have found set of neurons that mediate panic-like symptoms in mice, which showcase a novel brain pathway that could be a target for new panic disorder therapeutics.

Scientists develop a game-changing organoid model to study human cerebellar development and disease

Scientists have developed a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinj…

Surprise! — How the brain learns to deal with the unexpected

For children, the world is full of surprises. Adults, on the other hand, are much more difficult to surprise. And there are complex processes behind this apparently straightforward state of affairs. Researchers have been using mice to decode how reacti…

Using the body’s own cells to treat traumatic brain injury

Traumatic brain injuries (TBIs) can cause lasting damage, but stopping the rampant brain inflammation they cause is difficult. A team at the Wyss, @SEAS and @MGH led by Samir Mitragotri has made a new treatment using macrophages — immune cells that mi…

Complex, unfamiliar sentences make the brain’s language network work harder

Sentences with greater linguistic complexity are most likely to fire up a key brain language processing center, according to a study that employed an artificial language network.

Human beliefs about drugs could have dose-dependent effects on the brain

Mount Sinai researchers have shown for the first time that a person’s beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

Researchers identify new coding mechanism that transfers information from perception to memory

Our memories are rich in detail: we can vividly recall the color of our home, the layout of our kitchen, or the front of our favorite cafe . How the brain encodes this information has long puzzled neuroscientists.

Study identifies ‘visual system’ protein for circadian rhythm stability

Scientists have identified a protein in the visual system of mice that appears to be key for stabilizing the body’s circadian rhythms by buffering the brain’s response to light. The finding advances efforts to better treat sleep disorders and jet lag, …

Predicting Alzheimer’s dementia in oldest of the old

A new study indicates that severity of amyloid deposition in the brain — not just age — may be key to determining who will benefit from new therapies that delay the progression of Alzheimer’s disease.

Brain cell discovery sparks hope for fertility treatments

Researchers have demonstrated how a specific type of neuron in the brain affects the release of hormones that control ovarian function in females. These findings could help researchers understand and treat reproductive disorders in both animals and hum…