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Medications for patients with first episode psychosis may not meet guidelines

Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment, researchers have found.

Two studies unveil seizure prediction models in critically ill children

In a pair of studies, researchers describe innovative models for predicting seizure occurrence in critically ill children.

Two studies predict surgery outcomes for high-risk epilepsy patients

Anti-epileptic drugs control seizures and improve quality of life for most people with epilepsy. But for those who find medical treatment ineffective or intolerable, brain surgery is sometimes the next best option. Two studies explore the outcomes of b…

Optogenetics: Identifying new targets for intervention

The reliability of optogenetics as a method of intervention of temporal lobe seizures, and the role the cerebellum may play in hippocampal function and seizure reduction, have been the focus of recent study. Optogenetics is one of the hottest tools in …

Researchers explore genetic basis of early childhood epilepsies

A pair of studies provides innovative insights into the genetic underpinnings of childhood epilepsies. Technological advances in genetic analysis have uncovered changes in single genes that account for a surprising number of infantile and early-childho…

Depression in people who live in unhappy places experienced more than a week a month

People in the country’s unhappiest communities spend about a quarter of the month so far down in the dumps that it can harm their productivity, according to economists.

Disruptions in memory-related brain activity could inform new treatment strategies for smokers

Quitting smoking sets off a series of changes in the brain that Penn Medicine researchers say may better identify smokers who will start smoking again–a prediction that goes above and beyond today’s…

Brain network detected that gives humans superior reasoning skills

When it comes to getting out of a tricky situation, we humans have an evolutionary edge over other primates.

Neuroimaging study of anorexia nervosa finds that brain shrinkage is reversible

Their novel findings obtained by measuring “cortical thickness” for the first time in the eating disorder are now published in the renowned journal Biological Psychiatry.

Salience network linked to brain disorders

A brain structure called the insula is essential for selecting things out of the environment that are ‘salient’ for an individual, and dysfunction of this system is linked to brain disorders such as autism, psychosis and dementia.