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Location of strong sense of discomfort in brain found

Researchers have identified a new neural circuit in the brain which produces a strong sense of discomfort when activated. The discovery also allows them to show for the first time that the subthalamic nucleus, a structure in the brain that controls vol…

Research team discovers new role of cerebellum in coordinating the brain network essential for social recognition memory

Researchers discovered the cerebellum coordinates the brain network essential for social recognition memory. 

Rats have an imagination, new research suggests

Researchers have developed a novel system to probe a rat’s thoughts, finding that animals can control their brain activity to imagine remote locations.  

One sleepless night can rapidly reverse depression for several days

Most people who have pulled an all-nighter are all too familiar with that ‘tired and wired’ feeling. Although the body is physically exhausted, the brain feels slap-happy, loopy and almost giddy. Now, neurobiologists have uncovered what produces this p…

New clues to the mechanism behind treatment-resistant depression

Major depressive disorder (MDD) is a widespread mental health condition that for many is disabling. It has long been appreciated that MDD has genetic as well as environmental influences. In a new study researchers identify a gene that interacted with s…

What happens when we pass out? Researchers ID new brain and heart connections

Researchers have for the first time identified the genetic pathway between the heart and brain tied to fainting. They found that vagal sensory neurons trigger fainting, laying a foundation for addressing fainting-related disorders.

High metabolism is an early sign of Alzheimer’s disease

An early phase in the process of developing Alzheimer’s disease is a metabolic increase in a part of the brain called the hippocampus, report researchers.

DNA organization influences the growth of deadly brain tumors in response to neuronal signals

A pioneering study has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumor known as glioblastoma. Having identified the factors that glioblastoma uses to respond to neurons by growing and spreading, this…

The brain may learn about the world the same way some computational models do

New studies support the idea that the brain uses a process similar to a machine-learning approach known as ‘self-supervised learning.’ This type of machine learning allows computational models to learn about visual scenes based solely on the similariti…

Lab unlocks keys to alcohol withdrawal headache

Researchers have discovered mechanisms by which specific cells are activated in alcohol withdrawal-induced headache. The research may benefit further studies of various substance use disorder mechanisms including withdrawal. It may be possible to dev…