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From molecular to whole-brain scale in a simple animal, study reveals serotonin’s effects

With full genetic control and visibility into neural activity and behavior, scientists map out chemical’s role in behavior.

Dementia study reveals how toxic proteins spread through brain

Fresh insights into the spread of damaging proteins that build up in the brains of people with Alzheimer’s disease could hold the key to stopping the condition progressing, a study says.

Scientists discover a deadly brain cancer’s hidden weakness

The difficult-to-treat brain cancer glioblastoma steals a person’s mental faculties as it spreads, yet the tumor’s insidious ability to infiltrate neighboring networks in the brain could also prove its undoing.

FDA-approved Alzheimer’s drug lecanemab could prevent free-floating amyloid beta fibrils from damaging the brain

Researchers described the structure of a special type of amyloid beta plaque protein associated with Alzheimer’s disease (AD) progression. Scientists showed the small aggregates of the amyloid beta protein could float through the brain tissue fluid, re…

The brain reacts differently to touch depending on context

The touch of another person may increase levels of the ‘feelgood’ hormone oxytocin. But the context really matters. The situation impacts oxytocin levels not only in the moment, but also later.

Potential found to counter depression by restoring key brain rhythm

A new study in mice and rats found that restoring certain signals in a brain region that processes smells countered depression.

Researchers develop model for how the brain acquires essential omega-3 fatty acids

Researchers have developed a zebrafish model that provides new insight into how the brain acquires essential omega-3 fatty acids, including docosahexaenoic acid (DHA) and linolenic acid (ALA), with the potential to improve understanding of lipid transp…

Anti-depressant agent KNT-127 reduces stress as well as depression

Depression is a condition affecting millions across the globe. However, efficient drugs with minimal adverse effects are scarce. Now, researchers have reported how KNT-127, a delta opioid receptor agonist, quickly and efficiently reduces classic parame…

A special omega-3 fatty acid lipid will change how we look at the developing and aging brain

Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath.

Novel ultrasound uses microbubbles to open blood-brain barrier to treat glioblastoma in humans

In the first in-human clinical trial, scientists used a novel, skull-implantable ultrasound device to open the blood-brain barrier and repeatedly permeate large, critical regions of the human brain to deliver chemotherapy that was injected intravenousl…