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Serotonin 2C receptor associated with obesity and maladaptive behavior

A collaborative study reveals a new gene associated with obesity and maladaptive behavior. The evidence shows that rare mutations in the gene for the serotonin 2C receptor play a role in the development of obesity and dysfunctional behaviors in humans …

Newly identified neuromarker reveals clues about drug and food craving

Craving is known to be a key factor in substance use disorders and can increase the likelihood of future drug use or relapse. Yet its neural basis — or, how the brain gives rise to craving — is not well understood. In a new study, researchers from ha…

New support for a serotonin deficit in depression

Since the 1960s, researchers have postulated that major depression stems from disruptions in the serotonin neurotransmitter system, but the evidence for that idea, though plentiful, was indirect. In fact, a recent comprehensive analysis of existing stu…

Researchers map deep brain stimulation target for Alzheimer’s disease

Alzheimer’s disease (AD) is the fifth leading cause of death in adults over 65 years old. While many potential treatments for the neurodegenerative disease focus on developing drugs to target key culprits, a relatively new approach aims to more directl…

Racism takes its toll on brain and body

Structural racism has not only psychosocial but also biological consequences. Discrimination has been shown to contribute to mental and physical disorders including obesity, depression, and addiction, but the biological pathways from a social experienc…

Molecular hydrogen as a new strategy for the treatment of chronic pain

Researchers demonstrate in animal models that water enriched with hydrogen molecules (H2) improves the symptomatology of neuropathic pain and related emotional disturbances.

Exercise, mindfulness don’t appear to boost cognitive function in older adults

For decades, doctors and scientists have known that exercise is important for older adults — it can lower risk for cardiac issues, strengthen bones, improve mood and provide other benefits. Likewise, mindfulness training reduces stress, and stress can…

New immune culprit discovered in Alzheimer’s disease

Cerebrospinal fluid, the brain’s immune system, becomes dysregulated as we age and plays a newly discovered role in cognitive impairment in diseases such as Alzheimer’s, a new study has found.

Not-so private eyes: Eye movements hold clues to how we make decisions

New findings from mechanical engineers could, one day, help doctors screen patients for illnesses like depression or Parkinson’s Disease.

Subcutaneous fat emerges as a protector of females’ brains

Females’ propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopau…