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Honeycomb maze reveals role of hippocampus in navigation decisions

Researchers have discovered that the hippocampus creates a vector-based representation to support animals to make optimal navigation decisions. The researchers report results which go a long way to solving the problem of how hippocampal place cells con…

New imaging technique allows researchers to see gene expression in brains of live mice in real time

Scientists have developed a new technique for imaging mRNA molecules in the brains of living mice. The research reveals new insights into how memories are formed and stored in the brain and could allow scientists to learn more about diseases such as Al…

Nervous system workings related to PTSD, other mental health disorders

A new study measures changes in the human brain’s response to a perceived threat following non-invasive stimulation of the nervous system via the vagus nerve. The results have implications for the development of treatments for post-traumatic stress dis…

How immune response triggered by COVID-19 may damage the brain

A new study describes the immune response triggered by COVID-19 infection that damages the brain’s blood vessels and may lead to short- and long-term neurological symptoms. The study examined brain changes in nine people who died suddenly after contrac…

In Krabbe disease, neurons may bring about their own destruction

The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study. The discovery represents a new mechanism of action for the mutant gene, presenting a more accur…

Brain’s response to understanding stories changes as we grow up

Scientists have shown how our brain’s response to watching emotional and social stimuli in a movie changes between infancy and adulthood.

Connectivity of language areas unique in the human brain

Neuroscientists have gained new insight into how our brain evolved into a language-ready brain. Compared to chimpanzee brains, the pattern of connections of language areas in our brain has expanded more than previously thought.

When ASD occurs with intellectual disability, a convergent mechanism for two top-ranking risk genes may be the cause

Scientists have discovered a convergent mechanism that may be responsible for how two top-ranked genetic risk factors for autism spectrum disorder/intellectual disability (ASD/ID) lead to these neurodevelopmental disorders.

Complex post-traumatic stress disorder

The World Health Organization (WHO) recently listed a new diagnosis for complex post-traumatic stress disorder (CPTSD). Experts have now summarized the symptoms of the long-awaited new diagnosis and issued guidelines for clinical assessment and treatme…

Protecting the brain from dementia-inducing abnormal protein aggregates

Neurodegenerative diseases like Alzheimer’s and Parkinson’s are defined by pathogenic accumulation of toxic proteins in the brain. Now, however, scientists have established that the p62 protein, which is involved in cellular protein degradation, can pr…