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Immune cells drive congenital paralysis disease

Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the brain appears to play a major role by over-activating th…

Compelling new insights into dynamics of the brain’s serotonin system

A new study sheds new light on these big questions, illuminating a general principle of neural processing in a mysterious region of the midbrain that is the very origin of our central serotonin (5-HT) system, a key part of the nervous system involved i…

Awkward. Humans are still better than AI at reading the room

Humans are better than current AI models at interpreting social interactions and understanding social dynamics in moving scenes. Researchers believe this is because AI neural networks were inspired by the infrastructure of the part of the brain that pr…

Even light exercise could help slow cognitive decline in people at risk of Alzheimer’s

In a landmark clinical trial people at risk for Alzheimer’s who exercised at low or moderate-high intensity showed less cognitive decline when compared to those receiving usual care.

Exercise boosts brain health — even when energy is low

We know exercise is good for our body, but what about our brains? A new study suggests that exercise plays a crucial role in keeping our minds sharp, even when one of the brain’s key energy sources isn’t available. The study offers fresh insight into b…

What happens in the brain when your mind blanks

Mind blanking is a common experience with a wide variety of definitions ranging from feeling ‘drowsy’ to ‘a complete absence of conscious awareness.’ Neuroscientists and philosophers compile what we know about mind blanking, including insights from the…

How a smartphone app could transform mental health care

Smartphones may often feel like a source of stress, feeding us an endless stream of bad news and social comparison. But what if they could also be the solution? A team of researchers believes they can be. The team has developed a smartphone app that de…

Psychedelics can reverse neuroimmune interactions that boost fear

A new study suggests that fear and the immune system are connected in previously unknown ways. Researchers found that the immune system can influence stress and fear behaviors by changing how brain cells communicate.

Remembering the cold: Scientists discover how memories control metabolism

New multidisciplinary research shows that the brain forms memories of cold experiences and uses them to control our metabolism. The study shows that cold memories form in the brain — and map out how they subsequently drive thermoregulation. The discov…

A repurposed anti-inflammatory drug may help treat alcohol use disorder and related pain

A preclinical study finds that a drug already FDA-approved for treating inflammatory conditions may help reduce both alcohol intake and pain sensitivity — two issues that commonly co-occur with alcohol use disorder (AUD).