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‘The focea’: A region of improved vision in mice

Researchers have discovered that the visual cortex of mice contains a region of enhanced visual sensitivity dubbed the ‘focea’, making the mouse a better model of human vision than previously expected.

Researchers question prevailing Alzheimer’s theory with new discovery

Experts estimate more than 6 million Americans are living with Alzheimer’s dementia. But a recent study sheds new light on the disease and a highly debated new drug therapy.

Mouse brain imaged from the microscopic to the macroscopic level

Researchers have leveraged existing advanced X-ray microscopy techniques to bridge the gap between MRI (magnetic resonance imaging) and electron microscopy imaging, providing a viable pipeline for multiscale whole brain imaging within the same brain.

‘Unexciting’ an anxious brain: Novel drug reduces anxiety-like behavior in mice

Anxiety is considered a natural response to stress. However, a state of heightened anxiety, called anxiety disorder, prevents thousands of people from living their best lives. While several underlying mechanisms have been therapeutically targeted, much…

GluN3A knockout mouse: Alternative model for Alzheimer’s neurodegeneration

GluN3A-deficient mice display all aspects of Alzheimer’s neurodegeneration.

Saturated fatty acid levels increase when making memories

Saturated fatty acid levels unexpectedly rise in the brain during memory formation, according to new research.

Differences in human, mouse brain cells have important implications for disease research

A study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders.

Researchers find the adhesions that build the brain’s networks

Researchers have discovered a crucial protein involved in the communication and coordination between astrocytes as they build synapses in the brain. Lacking this molecule, called hepaCAM, astrocytes aren’t as sticky as they should be, and tend to stick…

A detailed atlas of the developing brain

Researchers have created a first detailed atlas of a critical region of the developing mouse brain, applying multiple advanced genomic technologies to the part of the cerebral cortex that is responsible for processing sensation. By measuring how gene a…

Marmoset study identifies brain region linking actions to their outcomes

The ‘anterior cingulate cortex’ is key brain region involved in linking behaviors to their outcomes. When this region was temporarily silenced, monkeys did not change behavior even when it stopped having the expected outcome. The finding is a step towa…