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Father with Alzheimer’s? You may be more at risk of brain changes

While some studies have suggested that having a mother with Alzheimer’s disease may put you more at risk of developing the disease, a new study finds that having a father with the disease may be tied to a greater spread of the tau protein in the brain …

Scientists map unprecedented detail of connections and visual perception in the mouse brain

In a massive scientific effort, hundreds of researchers have helped to map the connections between hundreds of thousands of neurons in the mouse brain and then overlayed their firing patterns in response to visual stimuli. This breakthrough is a critic…

Novel drug delivery platform paves way to potential new treatments for Alzheimer’s, other brain-related disorders

Researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer’s disease, multiple sclerosis, Parkinson’s disease and cancer…

New insights into neurodegeneration using human ‘mini brains’

Researchers have discovered a new way that neurons act in neurodegeneration by using human neural organoids — also known as ‘mini-brain’ models — from patients with frontotemporal lobar degeneration (FTLD). Understanding this new pathway could help r…

long-term effects of obesity on brain and cognitive health

With the global prevalence of obesity on the rise, it is crucial to explore the neural mechanisms linked to obesity and its influence on brain and cognitive health. However, the impact of obesity on the brain is complex and multilevel.

Scientists complete largest wiring diagram and functional map of the brain to date

From a tiny sample of tissue no larger than a grain of sand, scientists have come within reach of a goal once thought unattainable: building a complete functional wiring diagram of a portion of the brain.

Even under stress, male-female pairs had each other’s backs

When faced with a potential threat, mice often freeze in place. Moreover, when two animals are together, they typically freeze at the same time, matching each other’s periods of immobility. In a new study, researchers found that coordination during fea…

Groundbreaking study reveals changes in brain cell composition and gene activity in Tourette syndrome

In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have pinpointed exactly which cells are perturbed and how they malfunction, revealing how different types of brain cells are affected…

Childhood experiences shape the brain’s white matter with cognitive effects seen years later

Investigators have linked difficult early life experiences with reduced quality and quantity of the white matter communication highways throughout the adolescent brain. This reduced connectivity is also associated with lower performance on cognitive ta…

First insights into how excitatory and inhibitory brain signals change as people age using wearable scanner

A study has shown how aspects of brain function change with age, revealing that excitatory processes in the brain decrease, while inhibitory processes increase as children get older. The findings are an important step in understanding conditions like a…