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A new view of how the brain decides to make an effort

New research gives the first detailed view of ventral striatum activity during three phases of effort-based decision-making — the anticipation of initiating an effort, the actual execution of the effort and the reward, or outcome, of the effort.

What social distancing does to a fish brain

Researchers have discovered a brain molecule that functions as a ‘thermometer’ for the presence of others in an animal’s environment. Zebrafish ‘feel’ the presence of others via mechanosensation and water movements — which turns the brain hormone on.

The tree of cortical cell types describes the diversity of neurons in the brain

The tree of cortical cell types provides one of the most detailed and complete characterizations of the diversity of neural types in the brain so far.

Big data analysis suggests role of brain connectivity in epilepsy-related atrophy

An international study has found a link between the brain’s network connections and grey matter atrophy caused by certain types of epilepsy, a major step forward in our understanding of the disease.

Drinking blocks a chemical that promotes attention

Scientists studied the cascade of events that begins when alcohol diminishes norepinephrine release in a brain structure called the locus coeruleus.

COVID-19 may deepen depression, anxiety, and PTSD among pregnant and postpartum women

In a new study, researchers surveyed pregnant women and those who had recently given birth, finding concerning rates of depression, generalized anxiety and post-traumatic stress disorder (PTSD) symptoms, which were found to be exacerbated by COVID-19-r…

Novel mechanisms that cause protein clumping in brain diseases

A team of researchers has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer’s disease and several other neurodegenerative disorders.

Drug reverses age-related mental decline within days, mouse study shows

Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study. The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after …

Key molecules in brain development and neurodegenerative diseases identified

A research team uncovers the mechanism that regulates local expression of key molecules in brain development and neurodegenerative diseases.

Air pollution spikes linked to lower test scores for Salt Lake County third graders

More frequent exposure to air pollution spikes were associated with reduced test scores for third graders in Salt Lake County. Schools with a higher proportion of students of color and from households experiencing poverty were exposed to more peak poll…