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New targets for childhood brain tumors identified

People with the genetic condition neurofibromatosis type 1 (NF1) are prone to developing tumors on nervous system tissue. A new study has found that the development and growth of such tumors are driven by nearby noncancerous neurons and immune cells. T…

Improved neural probe can pose precise questions without losing parts of the answers

A technique for studying individual circuits in the brains of mice has been hampered because the light needed to stimulate neural activity briefly overwhelms the electrodes ‘listening’ for the response. Now, improved shielding within the neural probe e…

Scientists regenerate neurons in mice with spinal cord injury and optic nerve damage

Each year thousands of patients face life-long losses in sensation and motor function from spinal cord injury and related conditions in which axons are badly damaged or severed. New research in mice shows, however, that gains in functional recovery fro…

Protein mystery of three brain diseases unraveled

The accumulation of one particular protein in the brain is at the basis of three very different age-related conditions. Until recently, nobody understood how this was possible. Research now reveals that the shape of the protein determines the clinical …

Personality traits of patients with social anxiety disorder

Individuals with social anxiety disorder have markedly different personality traits than others. Emotional instability and introversion are hallmarks, according to a new study.

Alzheimer’s gene triggers early breakdowns in blood-brain barrier, predicting cognitive decline

Although scientists have long known APOE4 is a leading risk factor for Alzheimer’s disease, they were unsure how exactly it drives a decline in memory. Scientists believe they have now found an answer.

Implant-free optogenetics minimizes brain damage during neuronal stimulation

A minimally invasive optogenetic technique that does not require brain implants successfully manipulated the activity of neurons in mice and monkeys, researchers report. The researchers first genetically engineered neurons to produce a newly developed,…

Molecular switch plays crucial role in learning from negative experiences

Neurobiologists have discovered how the signalling molecule Neuromedin U plays a crucial role in our learning process. The protein allows the brain to recall negative memories and, as such, learn from the past.

Schizophrenia related to abnormal fatty metabolism in the brain

Researchers have discovered a deficiency in the brains of people with schizophrenia that could lead to the development of new drug therapies. A postmortem comparison revealed that schizophrenia was associated with lower than normal levels of S1P, a typ…

How the heart affects our perception

When we encounter a dangerous situation, signals from the brain make sure that the heart beats faster. When we relax the heart slows down. But the heartbeat also affects the brain but the underlying mechanisms are unclear. Researchers have now identifi…