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Gene therapy helps functional recovery after stroke

A new gene therapy turns glial cells — abundant support cells in the brain — into neurons, repairing damage that results from stroke and significantly improving motor function in mice.

A diabetes drug promotes brain repair — but it only works in females

Study finds that the diabetes drug metformin, known to promote brain repair, can also help restore cognitive function in adult mice but only in females and in a way that is dependent on the sex hormone estradiol.

Dynamic reorganization of brain circuit with post-stroke rehabilitation

Researchers have revealed an interaction between cortico-brainstem pathways during training-induced recovery in stroke model rats. The researchers demonstrated that the rapid compensatory recruitment of the cortex-to-brainstem pathways occurred when ot…

Universal code in our brains for what we find beautiful

A network in the human brain involved in inner thoughts and self-referential mental processing may contain a universal code for whether we find something to be beautiful.

Calcium channel blockers may be effective in treating memory loss in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have identified that calcium channel blockers may be effecti…

Discovering biological mechanisms enabling pianists to achieve skillful fingering

Researchers discovered a sensorimotor function integration mechanism that enables the skillful fingering of pianists. The group developed a system to produce tactile and proprioceptive sensation in the fingers with an electric current stimulator and an…

Direct link from brain’s emotion circuit to movement circuit

During high stress situations such as making a goal in soccer, some athletes experience a rapid decline in performance under pressure, known as ‘choking.’ Now, researchers have uncovered what might be behind the phenomenon: one-way signals from the bra…

Foot painters’ toes mapped like fingers in the brain

Using your feet like hands can cause organized ‘hand-like’ maps of the toes in the brain, never before documented in people, finds a new study of two professional foot painters.

Brain circuit controls individual responses to temptation in rats

Differences in a key brain circuit may suggest why some individuals are less able than others to resist tempting cues, according to a study in rats.

Regulator of first responder cells to brain injury

Researchers identified nuclear factor I-A (NFIA) as a central regulator of both the generation and activity of reactive astrocytes.