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Improved human brain organoids to boost neurological disease research

Research has optimized the process of making human brain ‘organoids’ — miniature 3D organ models — so they consistently follow growth patterns observed in the developing human brain. Researchers can use this reproducible experimental system to test d…

Was Mona Lisa’s smile a lie?

Using chimeric — or mirror — images, researchers have determined that one half of Mona Lisa’s smile displays happiness while the other half is neutral reflecting a non-genuine emotion.

Weak upper and lower body physical performance associated with depression and anxiety

Physical fitness is associated with a number of key health outcomes, including heart disease, cognition, mortality, and an overall feeling of well-being. A new study now links physical performance with mental health and emotions, suggesting that weak u…

How chronic inflammation may drive down dopamine and motivation

A new computational method will allow scientists to measure the effects of chronic inflammation on energy availability and effort-based decision-making. The method may yield insights into how chronic, low-grade inflammation contributes to motivational …

Children’s brains reorganize after epilepsy surgery to retain visual perception

Children can keep full visual perception — the ability to process and understand visual information — after brain surgery for severe epilepsy, according to a new study. A study of children who had undergone epilepsy surgery suggests that the lasting …

Tolerance to stress is a ‘trade-off’ as fruit flies age

With the help of the common fruit fly (D. melanogaster), which ages quickly because it only lives about 60 days, neuroscientists provide insights into healthy aging by investigating the effects of a foraging gene on age and stress tolerance.

Diabetes drug alleviates anxiety in mice

The antidiabetic medication metformin reduces anxiety-like behaviors in male mice by increasing serotonin availability in the brain, according to a new study. These findings could have implications for the treatment of patients with both metabolic and …

Which brain hemorrhage patients have treatable underlying conditions

A new study identifies patients more likely to have underlying lesions from brain-bleeds, a finding that could help doctors treat the condition more rapidly.

Brush your teeth — postpone Alzheimer’s

Researchers in Norway have discovered a clear connection between oral health and Alzheimer’s disease.

Low-amp electroconvulsive therapy may relieve suicidal thoughts

A new, small trial finds that low-amp electroconvulsive therapy is highly effective in reducing suicidal ideation while having no cognitive side effects.