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New insights into the aging brain

A group of scientists investigated why the choroid plexus contains so much more klotho than other brain regions.They showed that klotho functions as a gatekeeper that shields the brain from the peripheral immune system.

Mild blast forces cause brain pathology and deficits, despite lack of macroscopic damage

Using a rat model of bTBI, researchers show how even mild exposure to a single blast shock wave is able to induce small but potentially very meaningful pathogenic effects that accumulate with time. These effects, detected at the microscopic level, incl…

Scalpel-free surgery enhances quality of life for Parkinson’s patients

A high-tech form of brain surgery that replaces scalpels with sound waves improved quality of life for people with Parkinson’s disease that has resisted other forms of treatment, a new study has found.

Detecting schizophrenia before symptoms arise

A new study finds a neural signature that might help identify who will go on to develop schizophrenia. Earlier detection could improve outcomes.

Scientists solve century-old neuroscience mystery; answers may lead to epilepsy treatment

Scientists have solved a 125-year-old mystery of the brain, and, in the process, uncovered a potential treatment for acquired epilepsy. Perineuronal nets modulate electrical impulses in the brain, and, should the nets dissolve, brain seizures can occur.

Moving the motivation meter

Rats given the drug that reduced dopamine were much less likely to work for preferred morsels of food. But when these rats were then given one of the experimental drugs, they regained their motivation to work for the treat.

Navigating our thoughts: Fundamental principles of thinking

Humans think using their brain’s navigation system: Researchers combine individual threads of evidence to form a theory of human thinking.

Brain signature of depressed mood unveiled in new study

New research has identified a common pattern of brain activity that may be behind low mood feelings, particularly in people who have a tendency towards anxiety. The newly discovered network is a significant advance in research on the neurobiology of mo…

Brain activity pattern may be early sign of schizophrenia

Neuroscientists have identified a pattern of brain activity that is correlated with development of schizophrenia, which they say could be used as marker to diagnose the disease earlier.

Don’t stare! Monkey gaze study shows dopamine’s role in response inhibition

Researchers revealed the importance of the brain’s dopaminergic system for inhibiting already-planned actions. They trained monkeys to redirect their gaze towards targets newly presented on a screen, apart from when presented with signals to avoid such…