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Questioning the link between pollution by magnetite particles and Alzheimer’s disease

A 2016 study showed that exposure to urban pollution involving magnetite particles played a role in the development of Alzheimer’s disease. It began from the hypothesis that magnetite particles would generate chemical reactions that could cause oxidati…

Cells in ‘little brain’ have distinctive metabolic needs

‘Knocking out’ an enzyme that regulates the flow of fuel into mitochondria specifically blocks the development of the mouse cerebellum more than the rest of the brain.

Recognizing the uniqueness of different individuals with schizophrenia

Individuals diagnosed with schizophrenia differ greatly from one another. Researchers have demonstrated that very few identical brain differences are shared amongst different patients. Therefore, insights based on research at the group level (i.e. in t…

Creating custom brains from the ground up

Scientists describe a new way to create customized mouse models for studying the brain. After killing off young brain cells, the developing forebrain can then be reconstituted from genetically engineered stem cells containing the specific genetic modif…

Genetics of brain structure and description of largest human genetic study

New research describes the release of whole genome genetic data of 500,000 participants of the UK Biobank.

Brain circuits for successful emotional development established during infancy

Researchers tracking the development of the brain’s emotion circuitry in infancy found that adult-like functional brain connections for emotional regulation emerge during the first year of life. And the growth of these brain circuits during the second …

Neuron death in ALS more complex than previously thought

Researchers have discovered that two different kinds of motor neurons that die in people with ALS may die in different ways — an important insight for understanding the disease and, eventually, finding a cure.

Why depression, trauma can make you age faster

New research finds that the DNA of people with major depression is biologically older than that of people who do not have the condition.

Memory ‘brainwaves’ look the same in sleep and wakefulness

Identical brain mechanisms are responsible for triggering memory in both sleep and wakefulness, new research has shown.

Bipolar disorder: A good diet may boost treatment

Can diet impact the effectiveness of treatment for bipolar disorder, particularly in the case of depressive episodes? A new study addresses this question.