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Ketamine nasal spray could fight depression fast

Could a fast-acting new drug curb serious depression symptoms, including suicidal thoughts? A recent study says ‘yes,’ but questions of safety arise.

Workplace anxiety isn’t always a bad thing: It can boost performance

Researchers have developed a new comprehensive model of workplace anxiety. It includes triggers for anxiety in the workplace and its effect on employee performance.

‘Striosome’ neurons in the basal ganglia play a key role in learning

Researchers have successfully isolated and recorded the activity of a subset of neurons in the striatum in the brain, shedding light on one mechanism underlying learning and decision making in animals.

Possible novel method for stopping untreatable pediatric brain cancers

Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children. Scientists report testing th…

Researchers chart a new way to look at concussion

A research team studying concussion has published an interactive diagram showing the many facets of mild traumatic brain injury (TBI) — from sleep problems to mood disorders to the increased danger of dementia — and how they connect with and affect e…

Is whole-brain radiation still best for brain metastases from small-cell lung cancer?

A new study compares outcomes of 5,752 small-cell lung cancer patients who received whole-brain radiation therapy (WBRT) with those of 200 patients who received stereotactic radiosurgery (SRS), finding that the median overall survival was actually long…

Scientists uncover connection between post-natal sensory experiences and brain development

New research by neuroscientists sheds light on links between brain growth and sensations experienced by animals soon after birth. The researchers have identified a form of neural feedback in zebrafish that could link development of the body with that o…

Altered immune cells clear childhood brain tumor in mice

In mice, a fatal brainstem tumor was cleared by injecting it with engineered T cells that recognized the cancer and targeted it for destruction. The discovery is moving to human trials.

Innate immune adaptor TRIF confers neuroprotection in ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective ther…

Grafted brain organoids provide insight into neurological disorders

Scientists improve the growth of three-dimensional brain models to better understand autism, dementia, schizophrenia.