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Engineered microglia show promise for treating Alzheimer’s and other brain diseases

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer’s disease and other neurological disorders, according to scientists. By engineering human immune cells called microglia, the researchers have cre…

Father’s mental health can impact children for years

Five-year-olds exposed to paternal depression are more likely to have behavioral issues in grade school, researchers find.

How thoughts influence what the eyes see

A new study by biomedical engineers and neuroscientists shows that the brain’s visual regions play an active role in making sense of information.

Groundbreaking study uncovers how our brain learns

How do we learn new things? Neurobiologists using cutting-edge visualization techniques have revealed how changes across our synapses and neurons unfold. The findings depict how information is processed in our brain’s circuitry, offering insights for n…

Climate-related trauma can have lasting effects on decision-making

A new study suggests that climate trauma — such as experiencing a devastating wildfire — can have lasting effects on cognitive function.

How disturbed signaling pathways could promote epileptic seizures

Focal cortical dysplasia (FCD) type 2 is a congenital malformation of the cerebral cortex that is often associated with difficult-to-treat epilepsy. In the affected areas, nerve cells and their layer structures are arranged in an atypical manner, which…

Towards gene-targeting drugs capable of targeting brain diseases

Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex oligonucleotides (Chol-HDOs) enhance drug delivery to the brain. The…

Favorite music sets the brain’s opioids in motion

A new imaging study showed that listening to favorite music affects the function of the brain’s opioid system.

Brain areas necessary for reasoning identified

Researchers have identified the key brain regions that are essential for logical thinking and problem solving.

Researchers have mapped the hidden control system of vision

The smallest control system of vision in mammals has been mapped — a discovery that opens entirely new insights into how our vision works and how it can be affected by disease.