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Uncovering the secret of the hunger switch in the brain

Researchers have revealed the mechanism of action of the master switch for hunger in the brain: the melanocortin receptor 4, or MC4 receptor for short. They have also clarified how this switch is activated by setmelanotide (Imcivree), a drug recently a…

A neuromagnetic view through the skull

The brain processes information using both slow and fast currents. Until now, researchers had to use electrodes placed inside the brain in order to measure the latter. Researchers have now successfully visualized these fast brain signals from the outsi…

Estrogen status – not sex – protects against heightened fear recall

A new study shows that markers of fear recall differ between men and women, but in a hormone-dependent manner.

An ion pump to deliver chemotherapy agents to the brain

Despite surgery and subsequent treatment with chemotherapy and radiation, the majority of patients experience recurrence of malignant brain tumors. Researchers have shown in cells in culture that an ion pump can deliver drugs more accurately, which giv…

New measure to predict stress resilience

Researchers show that increased sensitivity in a specific region of the brain contributes to the development of anxiety and depression in response to real-life stress. Their study establishes an objective neurobiological measure for stress resilience i…

Cellular ‘hotspots’ in the brain may signify the earliest signs of cancer

Researchers have found small clusters of cells in the brain that identify locations where tumors could become malignant.

New study reveals brain basis of psychopathy

According to a new study, the structure and function of the brain areas involved in emotions and their regulation are altered in both psychopathic criminal offenders and otherwise well-functioning individuals who have personality traits associated with…

Brain regions responsible for intoxicating effects of alcohol

The slurred speech, poor coordination, and sedative effects of drinking too much alcohol may actually be caused by the breakdown of alcohol products produced in the brain, not in the liver as scientists currently think.

Get your head in the game — One gene’s role in cranial development

Researchers have found that certain cells in mouse craniums respond to increased expression of a gene called Dlx5 during early stages of embryonic development. They observed that a layer of these cells formed more bone and cartilage in mice engineered …

Power of light and oxygen clears Alzheimer’s disease protein in live mice

A small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the brains of Alzheimer’s disease patients. If perfected in humans, the technique could be used as an alternative appr…