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What is the link between sleep apnea and depression?

Researchers study the prevalence of sleep apnea in people with depression and suggest that it may explain why some depression treatments fail.

Do antidepressants work better than placebo?

A new paper asks whether there is sufficient evidence to prove that antidepressants work better than a placebo. They conclude that there is not.

What to know about Trintellix

Trintellix is an antidepressant that can help treat major depressive disorder. This article provides an overview of Trintellix, including its uses, how to take it, side effects, and drug interactions.

What to know about mirtazapine

Mirtazapine is a tetracyclic antidepressant that is available under the brand name Remeron. In this article, we provide an overview of mirtazapine, including its uses, side effects, warnings, and interactions.

Recognizing the hidden signs of depression

People with depression can experience a variety of symptoms, some of which may be harder to recognize than others. Hidden symptoms of depression can range from fatigue and changes in sleeping patterns to anger and losing interest in pleasurable activit…

Low-amp electroconvulsive therapy may relieve suicidal thoughts

A new, small trial finds that low-amp electroconvulsive therapy is highly effective in reducing suicidal ideation while having no cognitive side effects.

Researchers close in on a new depression mechanism

A study in rats identifies a key driver of anhedonia, the inability to experience pleasure. This finding may lead to new therapies not just for depression.

Depression: Esketamine trial leaves ‘more questions than answers’

A clinical trial for intranasal esketamine found it effective and safe for severe depression, leading to an FDA approval. But is this the end of the road?

How ketamine can change the brain to fight depression

New research in mice pinpoints some of the key mechanisms that ketamine triggers in the brain to fight the symptoms and characteristics of depression.

Can genetic variants predict depression risk in young people?

A new way of determining the genetic risk of depression may help predict which children and adolescents are most likely to face mental health problems.