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Novel method automates the growth of brain tissue organoids on a chip

A team of engineers and scientists has developed a new method for remote automation of the growth of cerebral organoids — miniature, three-dimensional models of brain tissue grown from stem cells.

Enzyme drives cognitive decline in mice, provides new target for Alzheimer’s

Researchers identify the PKC-alpha enzyme as a promising therapeutic target in Alzheimer’s disease; a mutation that increases its activity led to biochemical, cellular and cognitive impairments in mice.

Scientists capture detailed snapshots of mouse brain cells nibbling on neurons

The surprising findings point to another possible role for oligodendrocyte precursor cells.

Mom’s dietary fat rewires male and female brains differently

New findings in mice show that excessive weight gain while pregnant tips the scales for male but not female mice to be more depressed in adulthood due to less brain serotonin. A similar result was found in humans, where the more fat measured in a place…

Optically analyzing local brain environment: Astrocytes’ acid response in epileptic mice

Researchers have shown that astrocytes in the mouse brain exhibit an acid response with intensified epileptic seizures. The astrocytes’ acid response could lead to the amplification of excitatory neuronal signals and be the underlying drive for generat…

Wild primate study ties importance of social environment to molecular markers of age in the brain

A research team has demonstrated that, in a population of macaque monkeys, females with a higher social status had younger, more resilient molecular profiles, providing a key link between the social environment and healthy brains.

Neuroscientists discover a new drug candidate for treating epilepsy

Temporal lobe epilepsy (TLE) is one of the most common types of epilepsy worldwide. Although symptomatic medications are available, one-third of TLE patients remain unresponsive to current treatment, so new drug targets are critically needed. Neuroscie…

Pair of studies uncover surprising new roles for spinal cord and brainstem in touch

New research suggests spinal cord and brainstem are essential for processing touch signals as they travel to the brain

Drinking during pregnancy changes baby’s brain structure

A new MRI study revealed that consumption of alcohol even in low to moderate amounts during pregnancy can change the baby’s brain structure and delay brain development.

Can pharmacotherapies prevent alcohol use disorder in people with PTSD?

A research team showed how drugs can reduce alcohol preference in animal models of post-traumatic stress disorder.