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Heightened activity of specific brain cells following traumatic social experience blocks social reward and promotes sustained social avoidance

Past social trauma is encoded by a population of stress/threat-responsive brain cells that become hyperactivated during subsequent interaction with non-threatening social targets. As a consequence, previously rewarding social targets are now perceived …

For memory formation, organization matters

Researchers have found that cells in the rat hippocampus — a brain region that is essential for making memories — are specifically organized into small clusters when fear-based memories are formed. Furthermore, when rats slept after a learning period…

Key factors identified for regeneration of brain tissue

Researchers demonstrate in a zebrafish model that two proteins prevent scar formation in the brain, thereby improving the ability of tissue to regenerate.

Transcranial magnetic stimulation design goes deeper into brain

As a noninvasive neuromodulation method, transcranial magnetic stimulation (TMS) shows great potential to treat a range of mental and psychiatric diseases, including major depression. Current methods don’t go quite deep enough and are largely restricte…

The brain’s immune cells can be triggered to slow down Alzheimer’s disease

The brain’s big-eating immune cells can slow down the progression of Alzheimer’s disease.

New tools map seizures, improve epilepsy treatment

Two new models could solve a problem that’s long frustrated millions of people with epilepsy and the doctors who treat them: how to find precisely where seizures originate to treat exactly that part of the brain. By helping surgeons decide if and where…

How the brain processes language

Humans accomplish a phenomenal amount of tasks by combining pieces of information. We perceive objects by combining edges, categorize scenes by combining objects, interpret events by combining actions, and understand sentences by combining words. But r…

Brain cells use a telephone trick to report what they see

‘How many fingers am I holding up?’ For vision-sensing brain cells in a monkey’s visual cortex, that answer depends on whether the digits are next to each other or partially overlapping. A new study finds that single neurons conveying visual informatio…

Novel method automates the growth of brain tissue organoids on a chip

A team of engineers and scientists has developed a new method for remote automation of the growth of cerebral organoids — miniature, three-dimensional models of brain tissue grown from stem cells.

Enzyme drives cognitive decline in mice, provides new target for Alzheimer’s

Researchers identify the PKC-alpha enzyme as a promising therapeutic target in Alzheimer’s disease; a mutation that increases its activity led to biochemical, cellular and cognitive impairments in mice.