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Too much or too little sleep may make your body age faster

Both too little and too much sleep may be linked to faster aging throughout the body. Researchers analyzing 23 biological aging clocks found the lowest aging levels among people sleeping about 6.4 to 7.8 hours per day. Short or long sleep was also asso…

A major Alzheimer’s risk gene may shrink brain cells years before symptoms

Researchers have uncovered a possible reason why the Alzheimer’s risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. …

Schizophrenia’s lost brain connections follow a surprising pattern

Specialized brain scans reveal that schizophrenia is linked to widespread loss of the synapses that connect brain cells, with the left side of the brain hit especially hard. The damage follows a surprisingly organized pattern tied to the brain’s chem…

Scientists reveal how the brain changes its connections when uncertainty strikes

The brain has a remarkably flexible system for handling uncertainty and changing situations. Researchers found that the frontoparietal cortex constantly shifts how it communicates with other brain regions depending on what information is needed to make…

A therapy that “rewrites” childhood memories can ease fear of failure

Childhood criticism can leave people carrying a fear of failure long into adulthood, but new research suggests those emotional patterns may be surprisingly flexible. Young adults who revisited painful memories through imagery-based therapy showed lasti…

A little-known protein may be fueling Alzheimer’s — and scientists found a way to block it

An experimental Alzheimer’s compound prevented damaging protein clumps from forming in the brains of mice, helping nerve cells survive longer and reducing amyloid buildup. The treatment also appeared to improve heart health and slow some signs of agi…

A stress hormone may help the brain repair itself

A surprising stress-related signal may help the brain repair itself after injury. Researchers found that myelin-producing precursor cells rapidly release the stress hormone CRH near damaged brain tissue, helping control how those cells mature and rebui…

Ozempic may have revealed the brain’s hidden “craving center”

Ozempic-like drugs appear to weaken more than hunger—they may also reduce cravings for alcohol and other addictive substances. Scientists are increasingly tracing this effect to the lateral septum, a brain region that helps connect memories and surro…

Scientists discover a hidden brain rhythm that could improve Parkinson’s treatment

Scientists have pinpointed a brain network—and its distinctive electrical rhythm—that appears to drive the benefits of deep brain stimulation for Parkinson’s disease. The discovery could lead to more precise, personalized stimulation settings and…

Frequent cannabis users wake up with their “stress hormone” already elevated

Frequent cannabis users may wake up with unusually high levels of the stress hormone cortisol, suggesting their daily stress rhythms could be disrupted. Researchers say the finding raises questions about whether using cannabis for stress relief might, …