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Glial hyper-drive for triggering epileptic seizures

When epileptic patients suffer seizures, their brain is undergoing repetitive and excessive neuronal firing. But what triggers this has stumped scientists for years. Now, researchers have used fluorescence calcium sensors to track astrocytes’ role in e…

When thoughts flow in one direction

Contrary to previous assumptions, nerve cells in the human neocortex are wired differently than in mice. The study found that human neurons communicate in one direction, while in mice, signals tend to flow in loops. This increases the efficiency and ca…

Perfect balance: How the brain fine-tunes its sensitivity

A sensitive perception of the environment is crucial for guiding our behavior. However, an overly sensitive response of the brain’s neural circuits to stimuli can lead to neurodevelopmental disorders such as epilepsy. Researchers now report how neurona…

Scientists uncover 95 regions of the genome linked to PTSD

In posttraumatic stress disorder (PTSD), intrusive thoughts, changes in mood, and other symptoms after exposure to trauma can greatly impact a person’s quality of life. About 6 percent of people who experience trauma develop the disorder, but scientist…

Paper: To understand cognition–and its dysfunction–neuroscientists must learn its rhythms

Thought emerges and is controlled in the brain via the rhythmically and spatially coordinated activity of millions of neurons, scientists argue in a new article. Understanding cognition and its disorders requires studying it at that level.

Protecting brain cells with cannabinol

Scientists created four cannabis-derived CBN analogs (chemical look-a-likes) with enhanced neuroprotective properties and potential for therapeutic application in neurological disorders like Alzheimer’s, Parkinson’s, and traumatic brain injury. Their f…

Workings of working memory detailed

Investigators have discovered how brain cells responsible for working memory — the type required to remember a phone number long enough to dial it — coordinate intentional focus and short-term storage of information.

Exposure to air pollution during the first two years of life is associated with worse attention capacity in children

A growing body of research shows that exposure to air pollution, especially during pregnancy and childhood, may have a negative impact on brain development. Now a study has found that exposure to nitrogen dioxide (NO2) during the first two years of lif…

Following cellular lineage

Researchers have advanced the understanding of how the cerebral cortex develops by tracing the lineage of certain brain cells.

Teen stress may raise risk of postpartum depression in adults

A research team reports that social stress during adolescence in female mice later results in prolonged elevation of the hormone cortisol after they give birth.