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Promising MND drug helps slow disease progression and benefits patients physically

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.

Newly discovered barrier prevents immunity from reaching smell-sensing cells

Scientists have identified a previously unknown barrier that separates the bloodstream from smelling cells in the upper airway of mice. But this barrier ends up keeping some of the larger molecules of the body’s immune system out, and that may be hinde…

Attention and running influence individual brain cells independently

Neuroscientists have explored how individual neurons in mice are influenced by two different cognitive and behavioral states — attention and running. These two states were once thought to share a common mechanism. However, in a new study published tod…

Looking at images of people smiling at you extends antidepressant effects of ketamine, study finds

Simple computer-based neurocognitive training — using positive words and pictures designed to boost self-worth — prolongs the antidepressant effects of ketamine in people with treatment-resistant depression, researchers report.

How fear memories get stuck in some brains

Researchers have discovered a biological mechanism that increases the strength with which fear memories are stored in the brain. The study, done in rats, provides new knowledge on the mechanisms behind anxiety-related disorders, and identifies shared m…

Artificial intelligence used to uncover the cellular origins of Alzheimer’s disease and other cognitive disorders

Deep learning models represent ‘an entirely new paradigm for studying dementia.’

Drumming in woodpeckers is neurologically similar to singing in songbirds, study finds

Researchers have found regions in the woodpecker forebrain that show characteristics that until now have only been associated with vocal learning in animals and language in humans. The study shows that instead of being related to vocalization, activity…

How the brain develops: A new way to shed light on cognition

Researchers introduce a new neurocomputational model of the human brain that could bridge the gap in understanding AI and the biological mechanisms underlying mental disorders.

Scientists unearth another brain-shrinking mammal

A study of moles reveals that cold weather — not lack of food — drives the rare phenomenon of reversible brain shrinkage in mammals.

Molecular changes in the brain in the aftermath of a traumatic event may help explain long-term susceptibility or resilience

Social avoidance is a common symptom of PTSD, and scientists working to better understand why have laboratory evidence that while stress hormone levels consistently increase in the immediate aftermath of a traumatic event, there can be polar opposite c…