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Greater exposure to nitrogen dioxide linked to higher levels of biomarkers of Alzheimer’s disease in the brain

A study has found an association between air pollution and higher levels of deposition of beta-amyloid protein in the brain and of neurofilament light (NfL) in cerebrospinal fluid.

Realistic model of mouse hippocampus uncovers new mechanism for pattern separation

Our brains can distinguish highly similar patterns, thanks to a process called pattern separation. How exactly our brains separate patterns is, however, not full,y understood yet. Using a full-scale computer model of the dentate gyrus, a brain region i…

Parkinson’s disease mutation misdirects iron in the brain

A common gene mutation for Parkinson’s disease drives mislocalization of iron in activated microglia, according to a new study. The results may help explain the accumulation of toxic iron in affected brain areas in the disease and provide a basis for t…

Brain study on how to slow down climate change

When it comes to climate-friendly behavior, there is often a gap between what we want and what we actually do. Although most people want to see climate change slowed down, many do not behave in an appropriately sustainable way. Researchers have now use…

SARS-CoV-2 protein interacts with Parkinson’s protein, promotes amyloid formation, study finds

Researchers have shown that, at least in the test tube, the SARS-CoV-2 N-protein interacts with a neuronal protein called alpha-synuclein and speeds the formation of amyloid fibrils, pathological protein bundles that have been implicated in Parkinson’s…

When the brain switches from hearing to listening

What happens in the brain when simply hearing becomes listening? To answer this question, researchers have traced the neuronal fingerprint of the two types of sound processing in the mouse brain.

Learning and protecting itself: How the brain adapts

If there is an injury to the central nervous system such as after a stroke, the brain needs to compensate for this by reorganising itself. To do this, a dense network of molecules between the nerve cells — known as the extracellular matrix — must loo…

Your perception of self becomes blurrier over time

When you look at two objects close to you such as two leaves, it’s easy to tell them apart but when they are farther away from you, they become difficult to distinguish. The two objects become ‘compressed,’ a basic principle of perception. One’s concep…

New hope for people living with a genetic cause of autism

Researchers report they were able to ameliorate Fragile X syndrome symptoms after inserting the Fmr1 gene into the brains of very young transgenic mice that had been genetically engineered to lack this gene. When the researchers measured brain activity…

Asthma may reduce risk of brain tumors — but how?

Asthma has been associated with a lowered risk of brain tumors, and researchers now think they know why: Immune cells activated under conditions of asthma are less able to promote the growth of brain tumors. The findings could lead to new therapeutic a…