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Fine-tuning motivation in the brain

Neuroscientists have discovered a set of brain cells that influence the motivation of mice to perform tasks for rewards. Increasing the cells’ activity makes a mouse work harder or more vigorously. The neurons come with a feature that prevents the mous…

Researchers identify brain signals associated with OCD symptoms, paving way for adaptive treatment

The discovery of electrical signals in the brain associated with OCD could enable an emerging type of adaptive deep brain stimulation therapy as an improved treatment.

Better deep brain stimulation therapy for OCD

Researchers captured more than 1,000 hours of brain recordings from patients with OCD in the clinic and at home. These data are a key first step towards designing improved deep brain stimulation (DBS) treatments for neuropsychiatric disorders.

A new understanding of mental illness

The causes of psychiatric disorders are poorly understood. Now there is evidence that a wide range of early onset psychiatric problems (from depression, anxiety and addictions to dyslexia, bulimia, and ADHD) may be largely due to the combination of jus…

Does air pollution reduce the benefits of physical activity on the brain?

A new study shows that people who do vigorous physical activities, like jogging or playing competitive sports, in areas with higher air pollution may show less benefit from that exercise when it comes to certain markers of brain disease. The markers ex…

Coping with schizophrenia, when emotions can be too much

Psychologists have revealed a surprising finding that could help those who struggle with schizophrenia: While people with the illness tend to manage low-level negative emotions, they struggle to do so as those negative emotions increase.

Tau and PQBP1: Protein interaction induces inflammation in the brain

Researchers have clarified the relationship between the intracellular receptor PQBP1 and the structural protein Tau, which is dysregulated in neurodegenerative diseases such as Alzheimer’s disease. Tau was found to interact with PQBP1 in immune cells o…

MRI’s may be initial window into CTE diagnosis in living; approach may shave years off diagnosis

While chronic traumatic encephalopathy (CTE) cannot yet be diagnosed during life, a new study provides the best evidence to date that a commonly used brain imaging technique, magnetic resonance imaging (MRI), may expedite the ability to diagnose CTE wi…

Scientists find first in human evidence of how memories form

In a discovery that could one day benefit people suffering from traumatic brain injury, Alzheimer’s disease, and schizophrenia, researchers have identified the characteristics of more than 100 memory-sensitive neurons that play a central role in how me…

SARS-CoV-2 infects sustentacular cells in the olfactory epithelium of COVID-19 patients, study finds

The coronavirus does not appear to infect nerve cells in the olfactory epithelium and in the olfactory bulb, according to new research.