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Use it or lose it: Stopping exercise decreases brain blood flow

Researchers examined cerebral blood flow in master athletes (ages 50-80 years) before and after a 10-day period during which they stopped all exercise. Using MRI brain imaging techniques, they found a significant decrease in blood flow to several brain…

Vesicles that trap amyloid appear to also contribute to Alzheimer’s

Vesicles, fluid-filled sacs that brain cells make to trap amyloid, a hallmark of Alzheimer’s, appear to also contribute to the disease, scientists report. Reducing the production of these vesicles, called exosomes, could help reduce the amount of amylo…

Alzheimer’s: Nicotinic receptors as a new therapeutic target

Studies have indicated that nicotine may be beneficial for memory function. Scientists are set out to shed further light on the properties attributed to nicotine by determining the precise structure of the nicotinic receptors in the hippocampus region …

New window to understanding the brain

A team of researchers has demonstrated that syringe-injectable mesh electronics can stably record neural activity in mice for eight months or more, with none of the inflammation produced by traditional implanted probes.

Single gene mutation causes severely debilitating disease of brain blood vessels

The cause of a disease that targets blood vessels in the brain — leading to multiple debilitating symptoms and, often, to early death — has been tracked to a single mutated gene, opening up the immediate possibility of improved patient care through g…

Patients with moderate to severe TBI twice as likely to die from an unintentional injury

Research examining adults with moderate to severe TBI who participated in rehabilitation showed that they were twice as likely to die from an unintentional injury that occurred following their TBI. This was in comparison to individuals in rehabilitatio…

The brain performs feats of math to make sense of the world

Researchers have found that the brain is quite good at rapidly and subconsciously calculating the likelihood of various events, and remain flexible enough to account for new information. They traced these abilities to a region of the brain located just…

Replacing old memories with new for people who fear spiders

Triggering, interrupting, and resaving the memory of something unpleasant may help people to lose their phobia of spiders or other sources of anxiety.

Understanding the unhappy side of serotonin

Antidepressants improve mood by boosting serotonin levels, but serotonin can have negative effects, too. Scientists have been exploring why this happens.

Scientists uncover common cell signaling pathway awry in some types of autism

Skin cells derived from autistic donors grew faster than those from control subjects, and activated their genes in distinct patterns, scientists report. Genes related to cell growth were unusually active, leading to more cells but fewer connections bet…