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Sertraline, brand named Zoloft, improves functioning in young children with fragile X

Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of…

Marijuana use leads to laziness, study suggests

Rats given THC – a psychoactive compound in marijuana – were less willing to complete a difficult cognitive task in order to receive a greater reward.

Reducing prescription opioid addiction by switching receptors

Addiction to opioid painkillers has risen rapidly over the last decade. Could its addictive power be reduced by switching to a different receptor subtype?

Next steps in understanding brain function

As scientists around the globe join efforts to understand brain function, we enter the era of Big Data and stir up debate on how science is done and how it can affect us all.

Stiff arteries linked with memory problems, mouse study suggests

Using a new mouse model, researchers have found that stiffer arteries can also negatively affect memory and other critical brain processes. The findings may eventually reveal how arterial stiffness leads to Alzheimer’s and other diseases involving de…

Sights set on the next generation of shuttle peptides to target the brain

There is a new and emerging field of drug transporters that have the capacity to reach the brain more efficiently, say researchers, bringing together chemistry, pharmacy and biomedicine.

Psychosis associated with low levels of physical activity

A large international study of more than 200,000 people in nearly 50 countries has revealed that people with psychosis engage in low levels of physical activity, and men with psychosis are over two…

Disruptions to sleep patterns lead to an increased risk of suicides

The link between sleep problems and suicidal thoughts and behaviours is made starkly clear in new research from The University of Manchester, published in the BMJ Open.

In unstable times, the brain reduces cell production to help cope

People who experience job loss, divorce, death of a loved one or any number of life’s upheavals often adopt coping mechanisms to make the situation less traumatic.

Finally, the brain sensor that turns down the heat

At long last, researchers have zeroed in on the neurons that act as the brain’s internal thermostat.