Three studies examined cross-cultural differences in empathic accuracy (the ability to correctly infer another’s emotional experience) within the context of different relationships. East–West cultural differences in self-construal were hypothesized to differentiate levels of empathic accuracy across relationship types. In contrast to the independent self prevalent among members of Western cultures, members of Eastern cultures generally view the self as interdependent with those with whom they have a relationship. Easterners, relative to Westerners, are more concerned with the thoughts or feelings of close others and less concerned with the thoughts or feelings of those with whom they have no relational link (i.e., strangers). Across three studies, the authors found that East Asians, compared with European Americans, made more accurate inferences regarding the emotions of close others (i.e., friends), but less accurate inferences regarding the emotions of strangers. Furthermore, individual differences in interdependent self-construal among East Asians predicted the degree of empathic accuracy.