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New cable-free brain imaging method may take social neuroscience to the next level

May 28, 2019 by

Researchers developed a cable-free recording method that can measure brain activity associated with social behavior in mice. The method was based on a bioluminescent indicator of membrane voltage called 'LOTUS-V', which was delivered to cells via a gene expression system; it is therefore minimally invasive. LOTUS-V enabled cable-free detection of brain activity in freely moving mice. Activation in the primary visual cortex was found during social interaction.

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